uninterrupted night's sleep often leads to fatigue and upset. The study found that people who constantly disturbed sleep has six times more likely to have diabetes and heart disease. The new research explains that diabetes symptoms appear after three days of having trouble sleeping.
The new findings, published in the journal Nature Genetics helps to explain previous research, why night-shift workers are prone type 2 diabetes and heart disease.
By involving nearly 20,000 people, researchers found that people who had one of four variants of a particular gene six times higher risk of developing diabetes. Study participants whose sleep is interrupted repeatedly for three days will develop the symptoms of diabetes.
According to the researchers, damaged proteins known as MT2 may disrupt the biological clock or circadian rhythm and release the hormone insulin. These disorders lead to disruption in the regulation of blood sugar and lead to type 2 diabetes.
"Setting blood sugar is one of the many processes regulated by the body's biological clock. Study adds to our understanding of how genes play an important role in the regulation of the biological clock may influence the risk of diabetes. We found a very rare variant of the gene MT2 have much effect larger than the other variants are more common, "said Professor Philippe Froguel, from Imperial College London, as reported by dailymail, Tuesday (31/01/2012).
In 2008, a genetic study led by the same team found that people who have a common variation in the gene MT2 has a risk of developing type 2 diabetes is slightly higher.
The release of insulin responsible for the regulation of blood sugar levels known to be regulated by melatonin. While the body's sleep-wake cycle is controlled by melatonin had an effect in the form of drowsiness and lowering the body temperature.
"Genetic research such as this is useful because it can help us understand how genetics may influence a person's risk of type 2 diabetes. Risks are not controlled by a single gene., And we already know that other genetic changes as well as lifestyle factors may influence the likelihood of developing a complex condition, "said Dr Iain Frame, director of research at Diabetes UK.
The researchers are increasingly convinced that eating a balanced diet and enriched fruits and vegetables will keep the weight to stay healthy. Moreover, being more physically active can also help reduce the risk of type 2 diabetes as well as help patients with diabetes manage the disease more effectively and reduce the likelihood of more serious complications.
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